In 2021, the Centers for Disease Control and Prevention (CDC) predicted the number of drug overdose deaths was 109,179, and of that number, more than 82,000 could be attributed to opioids. The opioid epidemic complicates the workforce for employers, who must be prepared to legally and effectively navigate an addiction scenario. A few topics employers should address include drug testing, plans of action should an overdose event occur, and the signs of intoxication.